罗格列酮/Rosiglitazone,≥98% (HPLC)
- 产品编号：R0205
- 中文名称：罗格列酮/Rosiglitazone
- 英文名称：Rosiglitazone
- 英文别名:5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, Rosiglitazone
- CAS号:122320-73-4
- 分子式:C18H19N3O3S
- 分子量:357.43
- 纯度:≥98% (HPLC)
- MDL号:MFCD00871760
订货信息：
产品规格价格(RMB)
- R0205-100MG220
- R0205-1G980
性能描述
assay ≥98% (HPLC)
≥98% (HPLC)
form powder
solubility DMSO: ≥10 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions
Rosiglitazone is a potent agonist for PPARγ with an EC50 of 43 nM for the human receptor. It is antidiabetic, working as an insulin sensitizer by binding to the PPARγ receptors in fat cells and making the cells more responsive to insulin.
说明：
罗格列酮是一种强力的兴奋剂对于EC50的PPARγ43 nM 人类受体来说。作为胰岛素增感剂通过在脂肪细胞结合到PPARγ受体,使细胞对胰岛素的反应更迅速。
