丝裂霉素C/自力霉素/Mitomycin C,97%
- 产品编号：M0112
- 中文名称：丝裂霉素C/自力霉素/Mitomycin C
- 英文名称：Mitomycin C from Streptomyces caespitosus
- 英文别名:Mitomycin C from Streptomyces caespitosus
- CAS号:50-07-7
- 分子式:C15H18N4O5
- 分子量:334.33
- 纯度:97%
- MDL号:MFCD00078109
订货信息：
产品规格价格(RMB)
- M0112-2MG800
- M0112-5x2MG2500
- M0112-10x2MG4000
性能描述
| 试剂级别 |
BioReagent |
| form |
powder |
| solubility |
H2O: soluble4 mL/vial, clear to slightly hazy, blue to purple (Stock solutions should be filter sterilized and stored at 2-8 °C in the dark.) |
| suitability |
suitable for cell culture |
| storage temp. |
2-8°C |
别名：别名：丝裂霉素C; 自力霉素; 密吐霉素; 嘧吡霉素;MMC
Application
Mitomycin C is used to generate mitotically inactive feeder cells used in cell culture systems, such as mitotically inactive fibroblast used in embryonic stem cell (ESC) systems.
Biochem/physiol Actions
Inhibitor of DNA synthesis, nuclear division, and cancer cells. Antibacterial to gram positive, gram negative, acid-fast bacilli.
General description
Mitomycin C is an anti-neoplastic antibiotic, DNA inter-strand, cross-linking, alkylating agent that targets guanine nucleoside in the sequence 5′CpG-3′. It produces oxygen radicals and is preferentially toxic to hypoxic cells.
本品是从头状链霉菌培养液中分离提取的一种广谱抗肿瘤抗生素，对多种癌症有抗癌作用，其作用原理可使细胞的DNA解聚，同时阻碍DNA的复制，从而抑制肿瘤细胞分裂。
