苯甲基磺酰氟/PMSF/Benzylsulfonyl fluoride,≥98.5% (GC)
- 产品编号：P0106
- 中文名称：苯甲基磺酰氟/PMSF/Benzylsulfonyl fluoride
- 英文名称：Phenylmethanesulfonyl fluoride
- 英文别名:α-Toluenesulfonyl fluoride, Phenylmethylsulfonyl fluoride
- CAS号:329-98-6
- 分子式:C7H7FO2S
- 分子量:174.19
- 纯度:≥98.5% (GC)
- EC号:206-350-2
- MDL号:MFCD00007424
订货信息：
产品规格价格(RMB)
- P0106-1G50
- P0106-5G210
- P0106-10G380
- P0106-100G3000
性能描述
| 纯度 |
≥98.5% (GC) |
| solubility |
dry solvents (ethanol, methanol, and 2-propanol): soluble200 mM (Stock solution are stable for months at 4°C.) |
| |
H2O: unstable |
Application
Inhibits serine proteases such as trypsin and chymotrypsin. Also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase. Not as effective or as toxic as DFP. Effective concentration 0.1-1 mM. Half-life = 1 hr. at pH 7.5.
Biochem/physiol Actions
Administration of PMSF produces analgesia unrelated to its anticholinesterase effect, and prolongs the analagesic effect of centrally administered β-endorphin.
用途：生化研究。与羰基化合物缩合制备烯烃。胰蛋白酶、胰凝乳蛋白酶的抑制剂，可抑制丝氨酸蛋白酶例如胰蛋白酶(trypsin)和胰凝乳蛋白酶(chymotrypsin)，也可抑制半胱氨酸蛋白酶和乙酰胆碱酯酶。有效浓度为0.1-1mM。
中文名称: 苯甲基磺酰氟
英文名称: Phenylmethylsulfonyl fluoride
中文同义词: 苄磺酰氟、苄基磺酰氟、苯甲磺酰氟、苯磺基氟化物、苯甲基磺醯化氟、苯甲基磺酰氟化物
英文同义词: PMSF、Phenylmethylsulfonyl fluoride、alpha-Toluenesulfonyl fluoride、Benzenemethanesulfonyl fluoride
性状：白色至微黄色针状结晶或粉末。对湿敏感。难溶于水，且在水溶液中非常不稳定，容易分解。可溶于异丙醇、乙醇、甲醇、二甲苯和石油醚。有毒。有腐蚀性！
