盐酸土霉素/盐酸地霉素/盐酸氧四环素/Oxytetracycline hydrochloride/Ryomycin,≥95% (HPLC)
- 产品编号：O0101
- 中文名称：盐酸土霉素/盐酸地霉素/盐酸氧四环素/Oxytetracycline hydrochloride/Ryomycin
- 英文名称：Oxytetracycline hydrochloride
- 英文别名:Terramycin，BiosTAT，Cliimycin，Geomycin，Oxydyn，Oxycycline，Oxymycin，Ryomycin，Stevacin，TeTRAbon，Tetran
- CAS号:2058-46-0
- 分子式:C22H24N2O9 · HCl
- 分子量:496.89
- 纯度:≥95% (HPLC)
- EC号:218-161-2
- MDL号:MFCD00135815
订货信息：
产品规格价格(RMB)
- O0101-25G40
- O0101-100G110
- O0101-250G220
性能描述
| 试剂纯度 |
≥95% (HPLC) |
| form |
crystalline |
| color |
yellow |
| suitability |
suitable for 1694 per US EPA |
Application
Oxytetracycline is a tetracycline analog isolated from the actinomycete streptomyces rimosus. Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome-lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycopasma bovis isolates2. Product O5875 is ≥95% (HPLC), crystalline.
Biochem/physiol Actions
Oxytetracycline inhibits translation which results in cell death. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic so it can easily pass through a cell membrane and passively diffuses through channels in the bacterial membrane.
用途：特异性地与细菌核糖体30S亚基的A位置结合，抑制肽链的增长和影响细菌蛋白质的合成。
