性能描述

槲皮素标准品为100MG ,价格80

Biochem/physiol Actions

Quercetin is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle. Quercetin may also inhibit fatty acid synthase activity.

[物理性质] 黄色针状结晶（稀乙醇），在95-97℃成为无水物，在314℃（分解）。 1g溶于290ml沸乙醇，溶于冰醋酸，碱性水溶液显黄色，几乎不溶于水，乙醇溶液味道很苦。

槲皮素能显著抑制促癌剂的作用、抑制离体恶性细胞的生长、抑制艾氏腹水癌细胞DNA、RNA和蛋白质合成。槲皮素有抑制血小板聚集和5-羟色胺5-HT的释放作用。槲皮素对ADP、凝血酶和血小板活化因子PAF诱导的血小板聚集均有明显抑制作用其中对PAF的抑制作用最强槲皮素也能明显抑制凝血酶诱导的兔血小板3H-5-HT释放[西安金绿]。槲皮素不溶于水故导入亲水性基团增加溶解性便于吸收从而增强其药理作用。槲皮素氧乙酸赖氨酸盐水溶性增加。