环孢菌素A/环孢霉素A/环孢素/环孢多肽A/Cyclosporin A,≥98% (HPLC)
- 产品编号：C0165
- 中文名称：环孢菌素A/环孢霉素A/环孢素/环孢多肽A/Cyclosporin A
- 英文名称：Cyclosporin A
- 英文别名:Antibiotic S 7481F1, Cyclosporine
- CAS号:59865-13-3
- 分子式:C62H111N11O12
- 分子量:1202.61
- 纯度:≥98% (HPLC)
- MDL号:MFCD00274558
订货信息：
产品规格价格(RMB)
- C0165-250MG100
- C0165-1G350
- C0165-5G1200
性能描述
| 试剂纯度 | ≥98% (HPLC) |
| form | solid |
| color | white |
| 溶解性 | dichloromethane: soluble10 mg/mL |
| | ethanol: soluble10 mg/mL |
| | DMSO: soluble50 mg/mL |
| | chloroform: soluble6 mg/mL |
| | H2O: insoluble |
| 保存温度 | 2-8°C |
Biochem/physiol Actions
A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria.
