氯化血红素/卟啉铁/血卟啉/氯化高铁血红素/Hemin,≥98.0% (HPLC)
- 产品编号：H0111
- 中文名称：氯化血红素/卟啉铁/血卟啉/氯化高铁血红素/Hemin
- 英文名称：Chlorohemin
- 英文别名:Chlorohemin ;Hemin;Bovine
- CAS号:16009-13-5
- 分子式:C34H32ClFeN4O4
- 分子量:651.94
- 纯度:≥98.0% (HPLC)
- EC号:240-140-1
- MDL号:MFCD00010726
订货信息：
产品规格价格(RMB)
- H0111-1G50
- H0111-10G350
- H0111-100G2900
性能描述
| 生物来源 | from Porcine |
| 试剂级别 | 生化试剂 |
| 试剂纯度 | ≥98.0% (HPLC) |
| 保存温度 | 2-8°C |
Biochem/physiol Actions
Hemin, the oxidized version of heme, is an iron-containing prosthetic group for a diverse group of proteins. Free heme, which can be released from hemoglobin following hemolysis, is pro-inflammatory and contributes to iron-derived reactive oxygen species. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders.
Hemin may be used to study the expression and represson of heme oxygenase 1 (HO-1) as well as the activity of HO-1. Hematin is the X factor required to grown Haemophilus influenzae.
黑褐色片状结晶，不溶于水及醋酸，微溶于70%～80%乙醇，溶于稀氢氧化钠溶液，于氢氧化钠溶液中生成羟高铁血红素，溶于强有机碱(如三甲胺和二甲苯胺)和乙酸，溶于浓硫酸而失去铁，易溶于稀氨水；透射光为棕褐色， 反射光为钢蓝色，直至300℃也不熔化
生化研究；用作血检定染色剂；用于盐酸血卟啉制备
