姜黄素/Curcumin/姜黄色素/Diferulylmethane/Natural Yellow 3,~85%
- 产品编号:C0172
- 中文名称:姜黄素/Curcumin/姜黄色素/Diferulylmethane/Natural Yellow 3
- 英文名称:Curcumin
- 英文别名:(E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane
- CAS号:458-37-7
- 分子式:C21H20O6
- 分子量:368.38
- 纯度:~85%
- EC号:207-280-5
- MDL号:MFCD00008365
订货信息:
产品规格价格(RMB)
- C0172-20MG(标准品)360
- C0172-5G90
- C0172-25G390
- C0172-100G1260
性能描述
试剂纯度 | ~85% (HPLC) |
form | powder |
color | orange |
solubility | ethanol: soluble10 mg/mL |
| DMSO: >11 mg/mL |
| 0.5 M NaOH: soluble (then immediately dilute in PBS) |
保存温度 | −20°C |
Biochem/physiol Actions
A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity.1 Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
性状描述:
橙黄色结晶性粉末,溶于冰乙酸和乙醇,遇碱呈红棕色,遇酸呈浅黄色,不溶于水和乙醚
用途说明:
制造姜黄试纸,pH 8~9;测定硼
姜黄素为橙黄色结晶粉末,味稍苦。不溶于水,溶于乙醇、丙二醇,易溶于冰醋酸和碱溶液,在碱性时呈红褐色,在中性、酸性时呈黄色。对还原剂的稳定性较强,着色性强(不是对蛋白质),一经着色后就不易退色,但对光、热、铁离子敏感,耐光性、耐热性、耐铁离子性较差。
由于姜黄素分子两端具有两个羟基,在碱性条件下发生电子云偏离的共轭效应,所以当PH大于8时,姜黄素会由黄变红。现代化学利用此性能将其作为酸碱指示剂。