盐酸阿霉素/多柔比星/阿霉素/ADR/ADM/DOX/ 25MG,99.5% (HPLC)
- 产品编号：D0114
- 中文名称：盐酸阿霉素/多柔比星/阿霉素/ADR/ADM/DOX/ 25MG
- 英文别名:Hydroxydaunorubicin hydrochloride
- CAS号:25316-40-9
- 分子式:C27H29NO11 · HCl
- 分子量:579.98
- 纯度:99.5% (HPLC)
- EC号:246-818-3
- MDL号:MFCD00077757
订货信息：
产品规格价格(RMB)
- D0114-10MG180
- D0114-25MG300
- D0114-100MG900
性能描述
| 试剂纯度 | 99.5% (HPLC) |
| mp | 216 °C (dec.)(lit.) |
| 保存温度 | 2-8°C |
Biochem/physiol Actions
Antitumour antibiotic. Effect of adriamycin® on heart mitochondrial DNA;1 Properties.
Inhibitor of reverse transcriptase and RNA polymerase; immunosuppressive agent; intercalates in DNA.
Naturally fluorescent anthracycline antibiotic, anticancer drug. Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. Fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes.
盐酸阿霉素又名14-羟基柔红霉素;14-羟基正定霉素;羟基正定霉素 ,亚得利亚霉素, 亚德利亚霉素, 羟基柔红霉素, 羟基红比霉素,多柔比星,阿霉素.
橙红色疏松状块状物或粉末，易溶于水、DMSO、四氢呋喃、醇。不溶于丙酮、氯仿、苯、乙醚。水中溶解度10mg/ml。
