庆大霉素/硫酸庆大霉素/硫酸双生霉素/Gentamicin,>98%
- 产品编号:EQ0004
- 中文名称:庆大霉素/硫酸庆大霉素/硫酸双生霉素/Gentamicin
- 英文名称:Gentamicin sulfate salt
- 英文别名:Garamycin, Gentiomycin C
- CAS号:1405-41-0
- 纯度:>98%
- EC号:215-778-9
- MDL号:MFCD00270181
订货信息:
产品规格价格(RMB)
- EQ0004-1G75
- EQ0004-5G198
- EQ0004-10G319
性能描述
应用:
建议细胞培养使用50毫克/升
Used as a selection agent (gentamicin-resistance gene) in cell culture and molecular biology applications. Recommended for use in cell culture applications at 50 mg/L
生物活性:
Mode of action: Gentamicin causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site.1,2 The bactericidal effect of gentamicin on Pseudomonas aeruginosa is exerted by the binding of gentamicin to the outer membrane, where it displaces natural cations, destabilizes the membrane, and forms holes in the cell surface.3
抗菌谱:革兰氏阴性菌,金黄色葡萄球菌等革兰氏阳性细菌
试剂级别 | 生化试剂,植物组培试剂 |
性状 | 粉末 |
potency | >600 μg Gentamicin per mg |
solubility | H2O: soluble50 mg/mL (As stock solution, store at −20°C. Stable at 37°C for 5 days.), 在水中易溶,在乙醇、乙醚、丙酮或氯仿 |
suitability | suitable for cell culture |
storage temp. | 2-8°C |
主要成分:由小单孢菌所产生,为一种多组分抗生素
性状:常用其硫酸盐,为白色或类白色结晶性粉末;无臭;有引湿性。在水中易溶,在乙醇、乙醚、丙酮或氯仿
功能主治:对大肠杆菌、产气杆菌、克雷白杆菌、奇异变形杆菌、某些吲哚变形杆菌、绿脓杆菌、某些奈瑟菌、某些无色素沙雷杆菌和志贺菌等革兰阴性菌有抗菌作用。革兰阳性菌中,金黄色葡萄球菌对该品敏感;链球菌对该品耐药。厌氧菌、结核杆菌、立克次体、病毒和真菌亦对该品耐药。近年来,由于该品的广泛应用,耐药菌株逐渐增多,绿脓杆菌、克雷白杆菌和沙雷杆菌、吲哚阳性变形杆菌对该品的耐药率甚高。对金葡菌及大肠杆菌,产气杆菌,奇异变形杆菌,绿脓杆菌等G-菌作用较强。